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Axe
From Quake Wiki
Description
What the axe lacks in quality it makes up for in entertainment value! There are few things more satisfying then axe murdering someone, especially when the message is displayed for all on the server to see. This goes way below pummeling in Quake 3, which involves only a couple snuggles. It requires many whacks with the axe to defeat even an injured opponent, which makes pulling this off even more worth your while.
If you're using the axe, keep in mind that if you have any other weapon - I don't care what it is - you're making a big mistake. If you really do want to use it, though, or if you don't have anything else, you will surely meet your fate soon enough - but you may be able to get a couple of frags first, if you're careful enough. Try to attack the person from behind if possible. Once he turns to meet you, run to his back again. Basically, try to get as many whacks in without being in his line of fire. Any other weapon will surely kill you in a head-to-head skirmish, so don't let yourself get caught in one.
Fortunately for anyone being attacked by it, the axe is very easy to avoid. A few simple jumps when the person gets near you will assure that he won't be able to touch you. Just keep him in front of you as much as possible so you can shoot him. Chances are, he will become more of an annoyance than anything else. You may need some extra health afterward, but the chances of you dying are hardly phenomenal - unless you're hardly phenomenal yourself.
Effectiveness: Awful
Avoidability: Awful