From Quake Wiki
If they are even a concern, let them get moderately close and kill them with a shot from the Double-Barrelled Shotgun, that will take care of them most likely.
- Best Weapons: Double-Barreled Shotgun
- Worst Weapons: Grenade Launcher, Rocket Launcher, Thunderbolt (while underwater)
"Disgusting little critters who dish it out, but can't take it."